In the formal register, they are almost identical, minus some vocabulary choices. On one hand, you will find words that Europeans might find antiquated but are still commonly used in Québec (eg "barrer" vs "verrouiller", "soulier" vs "chaussure"), on the other you have many French words created in Québec for modern concepts for which France simply borrowed the English words (eg "courriel" vs "e-mail", "fin de semaine" vs "week-end"). So if you can read French from Paris, you can read French in Québec, with a few dictionary lookups now and then.
In the informal register, it is quite different. The way words are compressed/abbreviated, expressions, slang, swears, they are completely different. There is also a general difference in pronunciation. Not completely alien, but if you aren't used to it, it can be difficult to lock in at first.
Check out this video on an anglophone's view on Québec French after learning some France French: ▶Watch on YouTube
If you are in Canada (or have a VPN that can make it look like you are), there's also the Mauril site/app that teaches Québec French using archival footage from Radio-Canada.